妇幼微信服务号

(预约挂号)

妇幼健康号

Li Xiaotian
  • Academic level: doctoral supervisor
  • Professional title: chief physician, professor (dual titles)
  • Current position: president, Shenzhen Maternity and Child Healthcare Hospital
  • Main research directions: birth defects, high-risk pregnancy, perinatal medicine
Education

  Doctorate: Ph.D. in obstetrics and gynecology, Shanghai Medical College of Fudan University

  Clinical fellowships: Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong (computer applications in obstetrics); Department of Obstetrics, KK Women's and Children's Hospital, Singapore (prenatal diagnosis, high-risk pregnancy and maternal management); Department of Fetal Medicine, Children's Hospital of Philadelphia

  Executive education: EMBA Program, School of Management, Fudan University; Senior International Seminar on Health Development and Reform, Harvard University; Senior Executive Program in Hospital Management, University of Cambridge; Senior Executive Program in Hospital Management, Sciences Po, Paris


Work Experience

  Previous: resident, attending physician, associate chief physician, chief physician and professor in the Department of Obstetrics at the Obstetrics and Gynecology Hospital of Fudan University. Served as deputy director and director of the obstetrics department, and later as vice president overseeing medical services, education, research and human resources.

  Current: president, Shenzhen Maternity and Child Healthcare Hospital.


Academic Monographs

  Practical Midwifery (1st ed.), chief translator, People's Medical Publishing House, Beijing, 2018

  Fetal Medicine (2nd ed.), chief translator, People's Medical Publishing House, Beijing, 2013

  Pre-pregnancy Eugenics Guidance Manual, executive editor-in-chief, National Population and Family Planning Publishing House, Beijing, 2012

  Practical Pre-pregnancy Examination Manual, co-editor-in-chief (with Liang Huan), Shanghai Science and Technology Press, Shanghai, 2008

  Pathological Obstetrics, co-editor-in-chief (with Zhuang Yiliang), People's Medical Publishing House, Beijing, 2004

  Obstetrics and Gynecology (Essentials), chief editor, Fudan University Press, Shanghai, 2005

  Obstetrics and Gynecology (5-year digital edition), associate editor-in-chief, People's Medical Publishing House (forthcoming)

  Obstetrics and Gynecology (5-year program, 8th ed.), editorial board member, People's Medical Publishing House, January 2013

  Obstetrics and Gynecology (Planning Textbook for Higher Medical Education), editorial board member, Higher Education Press, October 2008

  Obstetrics and Gynecology (5-year program, 7th ed.), editorial board member, People's Medical Publishing House, January 2008

  Obstetrics and Gynecology (8-year program, 1st ed.), editorial board member, People's Medical Publishing House, August 2005

  Obstetrics and Gynecology (Graduate Textbook, 1st ed.), editorial board member, People's Medical Publishing House, September 2008

  Practical Obstetrics and Gynecology (4th ed.), associate editor-in-chief, People's Medical Publishing House, Beijing, 2018

  Practical Obstetrics and Gynecology (3rd ed.), associate editor-in-chief, People's Medical Publishing House, Beijing, 2012

  Practical Obstetrics and Gynecology (2nd ed.), editorial board member, People's Medical Publishing House, Beijing, 2003

  Modern Obstetrics, editorial board member, Science Press, Beijing, 2003

  Great Dictionary of China (Cihai) — Medical Science Volume, editorial board member, Shanghai Lexicographical Publishing House, Shanghai, 2003

  Clinical Microsurgery, editorial board member, Scientific and Technical Documents Publishing House, Beijing, 2002


Scientific Achievements

  First prize in Natural Science (principal investigator), 4th China Maternal and Child Health Awards, 2021

  Third prize, Shanghai Medical Award (principal investigator), 2009

  Fudan University Pukang Teaching Award (Obstetrics and Gynecology Teaching), 2008

  Fudan University Fuhua Teaching Award for Outstanding Graduate Advisor, 2008

  Nominated as Top 10 Clinical Rational Blood Use Expert, Shanghai Blood Management Office, 2008

  Second prize, Shanghai Outstanding Young Medical Stars (project leader: "Baroreflex Sensitivity Characteristics in Hypertensive Disorders of Pregnancy"), 2006

  National Elite Course Award for Medical Genetics (third contributor), 2006

  Named Model Pioneer of the Shanghai New Long March, 2001

  Second prize, 8th Silver Snake Award of the Shanghai Health System, 2001

  Third prize, Shanghai Science and Technology Progress Award (project leader: "Clinical and Experimental Research on the Pathophysiology of Fetal Distress"), 2000

  Third prize, Shanghai Science and Technology Progress Award (second contributor: "Hemodynamic and Pathophysiological Research on Hypertensive Disorders of Pregnancy in Elderly Primigravidas"), 1998

Honors & Awards

  Nomination Award, 7th Silver Snake Award of the Shanghai Health System, 1999

  Selected for Fudan University's inaugural "Century Star" Program for Outstanding Young Teachers, 2000

  Selected for the Shanghai Youth Science and Technology "Rising Star" Program, 2000

  Awarded second prize, 8th Silver Snake Award of the Shanghai Health System, 2001

  Selected for the "Century Star" Program, Fuhua Teaching and Research Reward Fund, 2003

  Selected for the New Century Excellent Talents Program, Ministry of Education, 2006

  Selected for the Shanghai Talent Development Fund, 2009

  Selected for the Shanghai Academic Discipline Leaders Program, 2012

  Selected for the Shanghai Leading Talents Program, 2012

  Designated as a "Medical Artisan" of Shanghai, 2021


Research Projects

  Dr. Li has led or contributed to more than 10 major national projects and over 30 research grants funded by National Natural Science Foundation of China (NSFC), Ministry of Health, Shanghai municipal programs, and Fudan University's 985 Program.

  Major and key projects

  Ministry of Science and Technology Key Project in Reproductive Health (2021-2025): Pathogenesis and prevention/control strategies for early-onset preeclampsia — chief principal investigator (PI) (27.73 million yuan)

  National Major Research Program (973 Program, 2014-2018): Molecular mechanisms of pregnancy-related diseases caused by abnormal maternal-fetal crosstalk — project PI (1 million yuan)

  National Key Basic Research Program (973 Program, 2009-2014): Basic research on the formation, development and treatment of congenital heart disease — subproject 4 leader: Pathogenesis of conotruncal malformations (5 million yuan)

  Ministry of Health Industry Research Project (2014-2019): Establishment and optimization of technical standards and guidelines for diagnosing and treating common high-risk fetuses — PI (500,000 yuan)

  National Key Clinical Specialty Construction Project (Obstetrics, 2010-2012): project leader (5 million yuan)

  Ministry of Education 985 Program Phase III (2011-2013): "Reproduction and Development" platform — core member (5 million yuan)

  National 10th Five-Year Plan Key Project (2005-2006): Prevention and treatment of hypertensive disorders in pregnancy and related coagulation complications — project leader (600,000 yuan)

  Ministry of Health Key Clinical Project (2007-2009): Study on prenatal intervention models for birth defects — project leader (900,000 yuan)

  Ministry of Health Key Clinical Project (2005-2007): Prenatal diagnosis methods and screening strategies for birth defects — project leader (900,000 yuan)

  China Medical Board (2005-2009): The prevention of high risk pregnancy and birth — PI ($350,000)

  National Natural Science Foundation of China Projects:

  NSFC grant (2020-2023): Role of coding circPRKCB in regulating trophoblast autophagy in preeclampsia pathogenesis — PI (560,000 yuan)

  NSFC grant (2018-2019): Mechanism of BPA-reprogrammed WNT-2 methylation in placental trophoblasts inducing preeclampsia-like changes in pregnant mice — PI (100,000 yuan)

  NSFC grant (2013-2017): Role of 14-3-3 and its DNA methylation regulation in preeclampsia pathogenesis — PI (700,000 yuan)

  NSFC grant (2009-2011): Role of TFPI-II in preeclampsia pathogenesis — PI (230,000 yuan)

  NSFC grant (2005-2007): Proteomic study on protein expression characteristics of placental trophoblasts in pregnancy-induced hypertension — PI (210,000 yuan)

  NSFC grant (1998-2001): Digital signal processing technology of fetal heart rate variability and its significance — PI (110,000 yuan)

  NSFC grant (1996-1998): Hemodynamic and pathophysiological changes during fetal distress and brain hypoxia in sheep models — PI (70,000 yuan)

  Other major projects:

  Shanghai Science and Technology Commission Key Project (2018-2020): Prevention and treatment strategies for advanced maternal age — PI (3 million yuan)

  Shanghai Talent Development Fund (2009-2011): First-trimester prenatal diagnosis strategies for Down syndrome — PI (100,000 yuan)

  Fudan University 985 Discipline Construction Subproject (2008-2010): Proteomic expression characteristics of placental trophoblasts in pregnancy-induced hypertension — PI (600,000 yuan)

  Shanghai Municipal Health Bureau Key Project (2008-2010): Novel techniques for prenatal diagnosis of birth defects — PI (150,000 yuan)

  Shanghai Science and Technology Commission Key Project (2007-2008): Animal models and comparative zoology study of impaired fetal stress response capacity — PI (380,000 yuan)

  Ministry of Health Fund (1998-2001): Digital signal processing technology of fetal heart rate variability and its clinical applications — PI (30,000 yuan)


Academic & Social Affiliations

  Professional societies: 2016-present: deputy head, Hypertensive Disorders in Pregnancy Working Group, Obstetrics and Gynecology Branch, Chinese Medical Association; 2015-2018: chairman, Perinatal Medicine Branch, Shanghai Medical Association; 2018-present: chairman, Expert Committee on Maternal and Infant Safety, Shanghai Municipal Health Commission; 2020-present: inaugural chairman, Special Committee on Maternal Safety, National Association for Maternal and Child Health Studies

  Editorial boards: 2015-present: associate editor-in-chief, Chinese Journal of Perinatal Medicine; 2016-present: associate editor-in-chief, Chinese Journal of Practical Gynecology and Obstetrics; 2017-present: associate editor-in-chief, Journal of Fudan University (Medical Sciences); 2016-present: editorial board member, Chinese Journal of Obstetrics and Gynecology; 2017-present: editorial board member, Acta Obstetricia et Gynecologica Scandinavica; 2021-present: editorial board member, Chinese Medical Journal